Rare Stem Cell Transplant Leads to Lasting HIV Remission in Norwegian Patient

A Norwegian patient has achieved long-term remission of HIV following a stem cell transplant for blood cancer. The donor was his brother, who carries a rare genetic mutation that blocks HIV from entering cells. Doctors originally performed the transplant to treat the cancer, not to cure HIV. Tests conducted after the procedure found no detectable virus and the patient remains off antiretroviral therapy with no viral rebound. Experts say this case adds to a small group worldwide showing sustained HIV remission after stem cell transplants. However, they caution that the procedure is high-risk and not a feasible cure for most people living with HIV. Researchers hope insights from this breakthrough will help develop safer, scalable approaches such as gene editing and targeted therapies.

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